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Hongsub Lee Selected Research

IDF-11774

11/2018Bcl-2-dependent synthetic lethal interaction of the IDF-11774 with the V0 subunit C of vacuolar ATPase (ATP6V0C) in colorectal cancer.
1/2017The novel hypoxia-inducible factor-1α inhibitor IDF-11774 regulates cancer metabolism, thereby suppressing tumor growth.
1/2016Identification of Targets of the HIF-1 Inhibitor IDF-11774 Using Alkyne-Conjugated Photoaffinity Probes.

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Hongsub Lee Research Topics

Disease

4Neoplasms (Cancer)
01/2020 - 01/2016
2Colorectal Neoplasms (Colorectal Cancer)
11/2018 - 01/2017
2Hypoxia (Hypoxemia)
01/2017 - 01/2016

Drug/Important Bio-Agent (IBA)

3IDF-11774IBA
11/2018 - 01/2016
15- (2,4- dihydroxy- 5- isopropylphenyl)- 4- (4- morpholin- 4- ylmethylphenyl)isoxazole- 3- carboxylic acid ethylamideIBA
01/2020
1Vacuolar Proton-Translocating ATPases (V-Type ATPase)IBA
11/2018
1Biomarkers (Surrogate Marker)IBA
11/2018
1Glucose (Dextrose)FDA LinkGeneric
01/2017

Therapy/Procedure

3Therapeutics
11/2018 - 01/2016